Cellular Biophysics
Our main interest is in the molecular mechanisms of photoreceptor signaling and increasingly in the mechanisms of neurodegeneration in certain retinal diseases.
![Aalto-yliopisto, liput / kuvaaja: Aino Huovio](/sites/g/files/flghsv161/files/styles/1_6_567w_354h_n/public/2018-04/new_undergraduates_31082015_photo_by_aino_huovio-6316_0.jpg?h=06d401b7&itok=CfTrnFKE)
Our research involves the use of genetically modified mice and the use and development of state-of-the-art electrophysiological recording techniques and approaches, from single-cell recording to electroretinography (ERG) across the isolated retina and in vivo ERG.
Presently our research is focused on two main areas:
- We study the molecular mechanisms controlling the gain and kinetics of photoreceptor signaling in various light conditions, especially the calcium-controlled feedback
- We aim at developing novel therapies for age-related macular degeneration (AMD).