Biomolecular Publications

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Selected Publications

Yin, Y., Roas-Escalona, N., and Linder, M.B. (2024) Molecular engineering of a spider silk and mussel foot hybrid protein gives a strong and tough biomimetic adhesive. Advanced Materials InterfacesDOI: 10.1002/admi.202300934

Fedorov. D., Roas Escalona, N., Tolmachev, D., Harmat, A., Scacchi, A., Sammalkorpi, M,Aranko, A.S., Linder, M.B. (2023) Triblock proteins with weakly dimerizing terminal blocks and an intrinsically disordered region for rational design of condensate properties Small, https://doi.org/10.1002/smll.202306817

Jonkergouw, Savola, P., Osmekhina, E., van Strien, Batys, P., and Linder, M.B. (2023) Exploration of Chemical Diversity in Intercellular Quorum Sensing Signalling Systems in Prokaryotes. Angew. Chem. Int. Ed. e202314469. doi/10.1002/anie.202314469.

Feng, J., Gabryelczyk, B., Tunn, I, Osmekhina, E, Linder, M.B., (2023) A mini-spidroin guides molecular design for cellular condensation mechanisms in S.cerevisiae ACS Synthetic Biology DOI: 10.1021/acssynbio.3c00374

Välisalmi, T, Bettahar, H., Zhou, Q., and Linder, M.B. (2023) Pulling and analyzing silk fibers from aqueous solution using a robotic device. International Journal of Biological Macromolecules 250, 126161. https://doi.org/10.1016/j.ijbiomac.2023.126161

Fan, R., Hakanpää, J., Elfving, K., Taberman, H., Linder, M.B., and Aranko, A.S. (2023) Biomolecular click reactions using a minimal pH-activated Catcher/Tag pair for producing native-sized spider-silk proteins. Angewandte Chemie International Edition 10.1002/anie.202216371

Välisalmi, T., Roas-Escalona, N., Meinander, K., Mohammadi. P., and Linder, M.B. (2023) Highly Hydrophobic Films of Engineered Silk Proteins by a Simple Deposition Method. Langmuir, doi.org/10.1021/acs.langmuir.2c03442

Jonkergouw, C., Beyeh, N.K., Osmekhina, E., Leskinen, K., Taimoory, M., Fedorov, D., Anaya-Plaza, E., Kostiainen, M., Trant, J.F., Ras, R.H.A., Saavalainen, P., and Linder, M.B. (2023) Repurposing host-guest chemistry to sequester virulence and eradicate biofilms in multidrug resistant Pseudomonas aeruginosa and Acinetobacter baumannii. Nature Communications. DOI 10.1038/s41467-023-37749-6 

Gabryelczyk, B., Sammalisto, F-E., Gandier, J-A., Feng, J., Beaune, G., Timonen, J.V.I., Linder, M.B. (2022) Recombinant protein condensation inside E. coli enables the development of building blocks for bioinspired materials engineering – Biomimetic spider silk protein as a case study. Materials Today Bio. https://doi.org/10.1016/j.mtbio.2022.100492 

Arola, S., Kou, Z., Rooijakkers, B.J.M., Velagapudi, R., Sammalkorpi, M., Linder, M.B. (2022) On the mechanism for the highly sensitive response of cellulose nanofiber hydrogels to the presence of ionic solutes Cellulose https://doi.org/10.1007/s10570-022-04664-w

Lemetti, L., Tersteegen, J., Sammaljarvi, J., Aranko, A.S., and Linder, M.B., (2022) Recombinant Spider Silk Protein and Delignified Wood Form a Strong Adhesive System.  ACS Sustainable Chemistry & Engineering 10, 1, 552–561,DOI: 10.1021/acssuschemeng.1c07043

Fedorov, D., Batys, P., Hayes, D.B., Sammalkorpi, M., and Linder, M.B.  (2020) Analyzing the weak dimerization of a cellulose binding module by analytical ultracentrifugation. International Journal of Biological Macromolecules. 163 1995-2004. 

Mohammadi, P., Aranko, A.S., Landowski, C.P., Ikkala, O., Jaudzems, K., Wagermaier, W., and Linder, M.B. (2019) Biomimetic composites with enhanced toughening using silk-inspired triblock proteins and aligned nanocellulose reinforcements. Science Advances 2019:5 eaaw2541

Lemetti, L., Hirvonen, S-P., Fedorov, D., Batys, P., Sammalkorpi, M., Tenhu, H., Linder, M.B., Aranko, S. (2019) Molecular crowding facilitates assembly of spidroin-like proteins through phase separation. European Polymer Journal 112, 539-546.

Osmekhina, E., Jonkergouw, C., Schmidt, G., Jahangiri, F., Jokinen, V., Franssila, S., Linder, M.B. (2018) Controlled communication between physically separated bacterial populations in a microfluidic device. Communications Biology 1:97 DOI: 10.1038/s42003-018-0102-y

Mohammadi, P., Aranko, A.S., Lemetti, L., Cenev, Z., Zhou, Q., Virtanen, S., Landowski, C.P., Penttilä, M., Fischer, W.J., Wagermaier, W., and Linder, M.B. (2018) Phase transitions as intermediate steps in the formation of molecularly engineered protein fibers. Communications Biology 1:86, DOI: 10.1038/s42003-018-0090-y

Arola S., Malho J.M., Laaksonen P., Lille M., Linder M.B. (2013) The role of hemicellulose in nanofibrillated cellulose networks. Soft Matter 9, 1319-1326.

Malho J-M., Laaksonen P., Walther A., Ikkala O., Linder M.B. (2012) Facile Method for Stiff, Tough and Strong Nanocomposites by Direct Exfoliation of Graphene into Native Nanocellulose Matrix. Biomacromolecules 13, 4, 1093–1099.

Laaksonen P., Walther A., Malho J-M., Kainlauri M., Ikkala O., Linder M.B. (2011) Genetic Engineering of Biomimetic Nanocomposites Using Diblock Proteins, Graphene and Nanofibrillated Cellulose. Angewandte Chemie International Edition 50, 37, 8688–8691

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